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By inhibiting Gwt1, Fosmanogepix disrupts the anchoring of mannoproteins on the fungal surface, impairing growth and pathogenicity through a mechanism distinct from azoles and echinocandins, thereby reducing the likelihood of cross-resistance (Pappas et al., 2023)

Because the body cant produce it naturally, B12 must come from diet or supplementation yet deficiency is increasingly common due to modern lifestyles and reduced absorption with age

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Slowly increase gentle fiber sources like cooked vegetables, oats, or applesauce to support digestion without making symptoms worse